The Science and Clinical Application of DNRS
The Dynamic Neural Retraining System is a structured neuroplasticity-based program designed to help people retrain neural patterns associated with nervous system sensitization, persistent physiological reactivity, and disruptive functional changes.
Healthcare provider referrals account for more than 30% of DNRS participants, highlighting the significant role clinicians play in helping patients access neuroplasticity-based interventions.
DNRS clinical resources are designed to help recognize patterns that may indicate nervous system sensitization and consider whether the program may be an appropriate intervention. Scroll down to explore the research, framework, and resources of DNRS.
Recent White Paper
Get the latest white paper on nociplasticity by DNRS founder Annie Hopper.
The paper explores how nervous system sensitization and maladaptive neuroplasticity may contribute to persistent symptoms, heightened physiological reactivity, and functional changes following an infection, injury, exposure or period of significant stress.
Clinical Referral Checklist
DNRS has been used by individuals experiencing a range of complex chronic conditions, particularly when central sensitization, persistent physiological reactivity, increasing sensitivity to triggers, and functional limitations are present.
The checklist below is intended as a clinical conversation aid to support consideration of DNRS as an appropriate neuroplasticity-based approach for a patient.
Interpreting the Checklist
DNRS may warrant further consideration when indicators are present across several areas (sensitization patterns, multisystem symptoms and functional impairment, meaning a reduced ability to perform daily activities due to symptoms) and appropriate medical assessment and treatment are already in place.
The presence of an individual symptom or diagnosis does not, by itself, establish suitability. Patient interest, expectations, readiness and ability to participate consistently should also inform the clinical conversation.
Research Supporting DNRS
Research conducted at McMaster University followed DNRS participants over a 12-month period and evaluated changes across multiple health and quality-of-life measures.
Participants reported significant improvements across multiple health and quality-of-life measures, providing encouraging evidence for the potential benefits of DNRS in people with complex chronic conditions.
White Paper on Nociplasticity
This white paper examines the potential role of a structured neuroplasticity-based intervention and a multidisciplinary approach to care.
DNRS is a self-directed educational program that teaches participants practical techniques intended to help change maladaptive neural patterns and support increased regulation, resilience and participation in daily life.
Clinicians can receive additional information about:
the structure of the DNRS program
patient participation and practice requirements
current and observational DNRS research
patient success stories and real-world outcomes
If you have questions about DNRS or how it can benefit your patient's recovery plan, please email us by clicking the button below.
